PCV Impact Assessment
Location
Sylhet District, Bangladesh
Background
This study in Sylhet district, Bangladesh, will evaluate the effectiveness of a 10-valent pneumococcal conjugate vaccine (PCV) against invasive disease.
Study Objectives
- Measure the rate of invasive (culture confirmed) pneumococcal disease (IPD) in the population before introduction of the PCV vaccine
- Measure the impact on clinical pneumonia, IPD, x-ray and ultrasound-confirmed pneumonia
- Measure the impact of PCV on nasopharyngeal carriage with Streptococcus Pneumoniae
- The study uses incidence trend and case-control study designs
Key Facts
- Bangladesh introduced PCV10 in March 2015 and we are continuing to study the impact of this vaccine in this population of children
Principal Investigator
Abdullah H. Baqui, JHSPH
Local Principal Investigator
Abdul Quaiyum, ICDDR,B
Funding
- Bill & Melinda Gates Foundation
- GlaxoSmithKline