ÎÚÑ»´«Ã½

Research

Our faculty engage in research, evidence synthesis, and methodology development, design, and coordination across a diverse array of health issues. Our faculty are experts in the conduct and optimization of clinical trials, conducting research activities and providing services that advance excellence in evidence-based health care. We serve as a coordinating center for highly complex, multi-site, and international trials, collaborating with peers to design, conduct, and synthesize high-quality studies across diverse disciplines. We invite peers and students to connect, collaborate, or consult with our faculty. Explore their individual areas of interest and ongoing projects. 

Our Work

Clinical trials

Our Center both conducts and coordinates clinical trials, observational studies, cohort studies, and more. Across diverse health care topics, our researchers and students investigate the safety and effectiveness of interventions and the variables that affect health. To connect with an expert in your area of interest or collaborate on a trial, explore our faculty research.  

Trial coordination

The Center serves as a coordinating center for complex, multi-site, and international trials, collaborating with peers around the world to design, conduct, and synthesize high-quality studies across an array of health topics. 

Evidence synthesis

Our Center conducts systematic reviews and meta-analyses of data and findings from published literature to synthesize findings and inform clinical practice. 

Methodology

Our faculty offer expertise in coordinating, applying, and developing conventional and innovative methodologies for conducting and reporting clinical trials and systematic reviews. We design, deploy, and teach the full spectrum of investigative methodologies related to clinical trials, evidence syntheses, and related reporting. Through the , our expert faculty consult with peers on study design, trial operations, and analysis plans.  

Graduate training

The Center offers graduate-level training within the Department of Epidemiology. Students can enroll in introductory and advanced courses in clinical trials, data management, and trial analysis techniques across a range of health care disciplines as well as courses in epidemiologic methods, systematic reviews, meta-analysis, and network meta-analysis. Learn more about the . 

Our Research

Design and conduct of clinical trials

  • Adaptive Trial Designs () 

  • Bias in conduct of systematic reviews and meta-analysis () 

  • Causal inference and outcome harmonization across multiple (interventional and observational) cohorts () 

  • Ethics of trials (, ) 

  • Graphical Techniques for Monitoring and Reporting Clinical Trials () 

  • Innovative methods for (interventional and observational) data coordinating centers () 

  • Registration and reporting guidelines (, ) 

  • Stakeholder engagement in research () 

  • State and nature of clinical trials () 

  • Streamlining Clinical Trials (, , ) 

Infectious diseases

  • Antibiotic-associated diarrhea () 

  • HIV/AIDS (, ) 

  • HPV () 

Lung and cardiovascular health

  • Asthma (, , ) 

  • COPD (, ) 

  • Stroke () 

Maternal and child health
  • Mother to Child Transmission of Hepatitis B () 
Mental health

  • Anxiety () 

  • Depression () 

Neurological health

  • Vestibular disorders () 

  • Dementia (, , ) 

Oncology
  • Oncology () 
Vision health
  • Eyes and vision (, , , , Sheriza Baksh) 
     
  • Uveitis (, , ) 

Collaborators

Center for Drug Safety and Effectiveness The Center for Drug Safety and Effectiveness serves as a nexus for individuals at Johns Hopkins who are involved in research, education, clinical programs and public service to improve prescription drug use and pharmaceutical policy.
Department of Epidemiology The Johns ÎÚÑ»´«Ã½ Department of Epidemiology is an internationally renowned academic center focused on educating future epidemiologists and generating fundamental and transformative knowledge to improve public health.
Evidence-based Practice Center The EPC produces comprehensive systematic reviews of important medical topics using interdisciplinary teams that integrate clinical expertise with expertise in evidence-based methods, collaborating with other EPCs and AHRQ programs.